Early detection of contrast-associated acute kidney injury after coronary angiography: A predictive value of osteopontin

doi:10.5527/wjn.v15.i2.116961

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Jun 25, 2026; 15(2): 116961
Published online Jun 25, 2026. doi: 10.5527/wjn.v15.i2.116961

Table 6 Correlations of osteopontin levels with other variables

Variables	Before PCI		After PCI
Variables	r	P value	r	P value
Age (years)	0.04	0.980	0.11	0.870
Body mass index (kg/m²)	0.10	0.450	0.09	0.270
SBP (mmHg)	-0.05	0.620	-0.08	0.470
DBP (mmHg)	-0.19	0.090	-0.09	0.390
Hemoglobin (g/dL)	-0.06	0.560	-0.02	0.840
Leucocytes (10³/μL)	0.11	0.560	0.13	0.490
Platelets (10³/μL)	0.09	0.200	-0.10	0.510
Serum creatinine (mg/dL)	0.45	0.001	0.42	0.001
Blood urea (mg)	0.23	0.040	0.30	0.020
eGFR (mL/minute/1.73 m²)	-0.33	0.030	-0.42	0.001
Alanine aminotransferase (U/L)	0.08	0.120	-0.11	0.890
Aspartate aminotransferase (U/L)	0.09	0.120	0.19	0.110
Bilirubin (mg/dL)	0.11	0.310	0.01	0.070
Albumin (g/dL)	0.21	0.560	-0.07	0.090
Glycosylated hemoglobin (%)	0.10	0.190	0.21	0.610
Cholesterol (mg/dL)	0.05	0.650	0.14	0.200
High-density lipoprotein (mg/dL)	0.14	0.210	0.24	0.400
Low-density lipoprotein (mg/dL)	-0.13	0.230	0.01	0.990
Triglyceride (mg/dL)	0.21	0.060	0.06	0.580
Troponin (ng/mL)	0.11	0.090	0.07	0.100
Creatine kinase (U/L)	0.09	0.100	0.11	0.380
CK-MB (ng/mL)	0.04	0.220	0.10	0.180
Aortic valve area (cm)	0.04	0.690	0.01	0.900
LVEDD (cm)	-0.01	0.870	-0.21	0.060
LVESD (cm)	0.12	0.560	0.09	0.760
Ejection fraction (%)	-0.18	0.210	-0.11	0.590
PASP (mmHg)	0.18	0.450	0.17	0.110
Amount of contrast (mL)	0.20	0.090	0.11	0.210
Mehran score	0.45	< 0.001	0.47	< 0.001

Data are presented as mean ± SD or n (%). SBP: Systolic blood pressure; DBP: Diastolic blood pressure; eGFR: Estimated glomerular filtration rate; CK-MB: Creatine kinase MB; PASP: Pulmonary artery systolic pressure; LVEDD: Left ventricular end diastolic pressure; LVESD: Left ventricular end systolic pressure; PCI: Percutaneous coronary intervention.

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Citation: Azoz NM, Nasr NG, Sobh MA, Abdel-Galeel A, Elzohne RA, Gadelkareem RA, Ahmed AO. Early detection of contrast-associated acute kidney injury after coronary angiography: A predictive value of osteopontin. World J Nephrol 2026; 15(2): 116961
URL: https://www.wjgnet.com/2220-6124/full/v15/i2/116961.htm
DOI: https://dx.doi.org/10.5527/wjn.v15.i2.116961

Azoz NM, Nasr NG, Sobh MA, Abdel-Galeel A, Elzohne RA, Gadelkareem RA, Ahmed AO. Early detection of contrast-associated acute kidney injury after coronary angiography: A predictive value of osteopontin. World J Nephrol 2026; 15(2): 116961 [PMID: 42395660 DOI: 10.5527/wjn.v15.i2.116961]

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