Alpha-1-microglobulin as an early biomarker in renal extrahepatic manifestations of hepatitis C virus infection

doi:10.5527/wjn.v15.i2.116866

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Jun 25, 2026; 15(2): 116866
Published online Jun 25, 2026. doi: 10.5527/wjn.v15.i2.116866

Table 5 Diagnostic ability of Urinary alpha-one-microglobulin to differentiate between patients with hepatitis C virus and controls

Indices	Urinary alpha-one-microglobulin
AUC (95%CI)	0.864 (0.801-0.913)
Optimal cut off	> 3.52 mg/L
Accuracy	77.0%
Sensitivity	60.0%
Specificity	93.7%
Positive predictive value	90.4%
Negative predictive value	69.8%
P value	< 0.001

AUC: Area under the curve; CI: Confidence interval.

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Citation: Alkareemy EAR, Azoz NM, Abdelnaiem GS, Gadelkareem RA, Saleh KA, Abdel Aziz EM. Alpha-1-microglobulin as an early biomarker in renal extrahepatic manifestations of hepatitis C virus infection. World J Nephrol 2026; 15(2): 116866
URL: https://www.wjgnet.com/2220-6124/full/v15/i2/116866.htm
DOI: https://dx.doi.org/10.5527/wjn.v15.i2.116866

Alkareemy EAR, Azoz NM, Abdelnaiem GS, Gadelkareem RA, Saleh KA, Abdel Aziz EM. Alpha-1-microglobulin as an early biomarker in renal extrahepatic manifestations of hepatitis C virus infection. World J Nephrol 2026; 15(2): 116866 [PMID: 42395679 DOI: 10.5527/wjn.v15.i2.116866]

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