Factors associated with acute kidney injury in rhabdomyolysis: Insights from a prospective study

Table 4 Baseline laboratory data and McMahon score of patients with rhabdomyolysis: Comparison between those who developed acute kidney injury and those who did not, mean ± SD/median (25^th-75^th percentiles)

Variables	All patients (n = 54)	AKI group (n = 28)	Non-AKI group (n = 26)	P value
CPK (UI/L)	2151 (1340-3729)	2868 (1410.7-9178.2)	2004 (1216-2426.7)	0.04
LDH (U/L)	580 (315-95)	877.5 (665.5-1793)	321.5 (286-406.7)	< 0.001
Corrected serum calcium (mmol/L)	2.3 ± 0.1	2.32 ± 0.2	2.3 ± 0.1	0.562
Phosphorus level (mmol/L)	1.07 ± 0.6	1.2 ± 0.8	0.82 ± 0.2	0.024
Serum bicarbonate (mmol/L)	22.25 ± 4.3	20.1 ± 4.2	24.5 ± 3.3	< 0.001
Urea (mmol/L)	6.8 (5-11.6)	10 (6.8-15.2)	4.9 (3.2-6.5)	0.001
Serum creatinine, (μmol/L)	82.5 (63.8-152.8)	149.4 (97.5-189)	66 (50.7-81.4)	< 0.001
Potassium level (mmol/L)	4.15 ± 0.8	4.3 ± 0.8	3.9 ± 0.6	0.147
Albumin level (g/L)	27.92 ± 5.1	26.3 ± 5.8	29.7 ± 3.6	0.017
AST (UI/L)	80 (55-178)	139 (69.5-202)	58.5 (44-94)	< 0.001
ALT (UI/L)	38.5 (23-76.5)	51.5 (27-91)	25 (20-44)	0.038
Total cholesterol (mmol/L)	3.65 ± 1.2	3.7 ± 1.5	3.5 ± 0.7	0.439
LDLc (mmol/L)	2.4 ± 1.1	2.4 ± 1.4	2.3 ± 0.7	0.724
Glycemia (mmol/L)	7.34 ± 3.7	8.1 ± 4.2	6.5 ± 2.8	0.126
C-reactive protein (mg/L)	150.61 ± 113.1	167.6 ± 128.7	132.3 ± 92.3	0.255
Hemoglobin (g/dL)	10.1 ± 2.2	9.9 ± 2.2	10.2 ± 2.05	0.674
White blood cells per liter	14776.8 ± 5970.2	14935.4 ± 6865.4	14606.2 ± 4960	0.842
Prothrombin time (%)	67.17 ± 18.5	60.6 ± 16.8	74.2 ± 18	0.006
McMahon score	5.78 ± 3	7.2 ± 3.9	4.1 ± 1.39	< 0.001

CPK: Creatinine phosphokinase; LDH: Lactate dehydrogenase; AST: Aspartate transaminase; ALT: Alanine transaminase; LDLc: Low-density lipoprotein cholesterol; AKI: Acute kidney injury.