Factors associated with acute kidney injury in rhabdomyolysis: Insights from a prospective study

doi:10.5527/wjn.v15.i2.110379

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Prospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Jun 25, 2026; 15(2): 110379
Published online Jun 25, 2026. doi: 10.5527/wjn.v15.i2.110379

Table 2 Baseline demographic characteristics and comorbidities of patients with rhabdomyolysis: Comparison between those who developed acute kidney injury and those who did not, n (%)/mean ± SD

Variables	All patients (n = 54)	AKI group (n = 28)	Non-AKI group (n = 26)	P value
Age (years)	46.1 ± 17.9	50.2 ± 17.3	41.8 ± 17.8	0.087
Gender				0.381
Male	43 (79.6)	21 (75)	22 (84.6)
Female	11 (20.4)	7 (25)	4 (15.4)
Smoking	35 (64.8)	16 (57.1)	19 (73.1)	0.221
Comorbidities
Diabetes	10 (18.5)	8 (28.6)	2 (7.7)	0.05
Dyslipidemia	14 (25.9)	11 (39.3)	3 (11.5)	0.02
Hypertension	14 (25.9)	9 (32.1)	5 (19.2)	0.279
Coronary artery disease	10 (18.5)	4 (14.3)	6 (23.1)	0.406
Chronic heart failure	4 (7.4)	3 (10.7)	1 (3.8)	0.336
Chronic kidney disease	3 (5.6)	2 (7.1)	1 (3.8)	0.597
Regular treatment before admission to the intensive care unit
Oral antidiabetics	6 (11.1)	4 (14.3)	2 (7.7)	0.44
Insulin therapy	6 (11.1)	5 (17.9)	1 (3.8)	0.114
Statin	13 (24.1)	8 (28.6)	5 (19.2)	0.422
Renin-angiotensin system blockers	5 (9.3)	2 (7.1)	3 (11.5)	0.464
Oral furosemide	6 (11.1)	3 (10.7)	3 (11.5)	0.629
Causes of rhabdomyolysis				0.001
Traumatic	23 (42.6)	6 (21.4)	17 (65.4)
Non traumatic	31 (57.4)	22 (78.6)	9 (34.6)

AKI: Acute kidney injury.

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Citation: Ghabi H, Smai A, Tlili S, Rais L, Ben Hmida F, Mesbahi B, Bounaouas I, Mami I, Messaoudi Y, Zouaghi MK. Factors associated with acute kidney injury in rhabdomyolysis: Insights from a prospective study. World J Nephrol 2026; 15(2): 110379
URL: https://www.wjgnet.com/2220-6124/full/v15/i2/110379.htm
DOI: https://dx.doi.org/10.5527/wjn.v15.i2.110379

Ghabi H, Smai A, Tlili S, Rais L, Ben Hmida F, Mesbahi B, Bounaouas I, Mami I, Messaoudi Y, Zouaghi MK. Factors associated with acute kidney injury in rhabdomyolysis: Insights from a prospective study. World J Nephrol 2026; 15(2): 110379 [PMID: 42395664 DOI: 10.5527/wjn.v15.i2.110379]

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