Efficacy and safety of finerenone in diabetic kidney disease: Latin American experience from FINDKDLATAM trial

doi:10.5527/wjn.v15.i1.115933

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World Journal of Nephrology

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2220-6124

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Mar 25, 2026; 15(1): 115933
Published online Mar 25, 2026. doi: 10.5527/wjn.v15.i1.115933

Table 3 Comparison of baseline and final paraclinical parameters stratified by age range, median (interquartile rage)

	Baseline	Final	P value
< 65 years
HbA1c	7.8 (6.9-8.3)	7.1 (6.5-7.9)	0.0000
eGFR	42 (30-50)	44 (27-51)	0.3656
ACR	352 (189-750)	90 (29-194)	0.0000
SBP	142 (130-160)	130 (120-140)	0.0000
DBP	78 (70-84)	74 (70-80)	0.0000
Potassium	4.4 (4.0-4.6)	4.6 (4.3-5.0)	0.0000
65-79 years
HbA1c	7.5 (6.7-8.1)	7.0 (6.5-7.9)	0.0027
eGFR	38 (29-49)	40 (29-55)	0.7439
ACR	327 (197-850)	86 (33-150)	0.0000
SBP	145 (134-160)	130 (120-140)	0.0000
DBP	80 (70-82)	72 (70-80)	0.0000
Potassium	4.4 (4.1-4.7)	4.8 (4.4-5.0)	0.0000
≥ 80 years
HbA1c	7.0 (6.4-7.7)	6.9 (6.4-7.0)	0.3292
eGFR	33 (30-50)	32 (27-55)	0.9365
ACR	297 (85-430)	27 (23-125)	0.0003
SBP	130 (124-150)	120 (118-130)	0.0928
DBP	77 (69-80)	70 (64-80)	0.4048
Potassium	4.5 (4.1-4.8)	4.8 (4.5-5.1)	0.0512

HbA1c: Glycated hemoglobin A1c; eGFR: Estimated glomerular filtration rate; ACR: Albuminuria/creatinuria ratio; SBP: Systolic blood pressure; DBP: Diastolic blood pressure.

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Citation: Arnedo RD, Polo VS, Garcia JB, Gutiérrez JF, Clason ER, Domínguez D, Rebutti GM, Mancia CM, López RT, Meza MR, López DT, Muñoz Zambrano JJ, Herrera EL, Dina-Batlle E, Terrones MC, de Moraes TP, Yánez TR, Osorio W, Cabeza AA, Rico-Fontalvo J. Efficacy and safety of finerenone in diabetic kidney disease: Latin American experience from FINDKDLATAM trial. World J Nephrol 2026; 15(1): 115933
URL: https://www.wjgnet.com/2220-6124/full/v15/i1/115933.htm
DOI: https://dx.doi.org/10.5527/wjn.v15.i1.115933

Arnedo RD, Polo VS, Garcia JB, Gutiérrez JF, Clason ER, Domínguez D, Rebutti GM, Mancia CM, López RT, Meza MR, López DT, Muñoz Zambrano JJ, Herrera EL, Dina-Batlle E, Terrones MC, de Moraes TP, Yánez TR, Osorio W, Cabeza AA, Rico-Fontalvo J. Efficacy and safety of finerenone in diabetic kidney disease: Latin American experience from FINDKDLATAM trial. World J Nephrol 2026; 15(1): 115933 [PMID: 41884241 DOI: 10.5527/wjn.v15.i1.115933]

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