Efficacy and safety of finerenone in diabetic kidney disease: Latin American experience from FINDKDLATAM trial

doi:10.5527/wjn.v15.i1.115933

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Nephrol. Mar 25, 2026; 15(1): 115933
Published online Mar 25, 2026. doi: 10.5527/wjn.v15.i1.115933

Table 2 Comparison of baseline and final paraclinical parameters in total sample and stratified by finerenone dosage, median (interquartile rage)

	Baseline	Final	P value
General
HbA1c	7.6 (6.8-8.1)	7.0 (6.5-7.9)	0.0000
eGFR	39.0 (30.0-50.0)	41.6 (27.0-52.0)	0.7209
ACR	345 (189-760)	81 (28-167)	0.0000
SBP	143 (130-160)	130 (120-140)	0.0000
DBP	79 (70-82)	73 (70-80)	0.0000
Potassium	4.4 (4.1-4.7)	4.7 (4.3-5.0)	0.0000
Dosage 10
HbA1c	7.8 (7.0-8.1)	7.2 (6.5-8.0)	0.0002
eGFR	33 (28-43)	30 (26-43)	0.0104
ACR	430 (257-898)	90 (24-186)	0.0000
SBP	145 (135-160)	130 (120-133)	0.0000
DBP	80 (70-87)	70 (65-80)	0.0000
Potassium	4.5 (4.2-4.8)	5.0 (4.6-5.2)	0.0000
Dosage 20
HbA1c	7.3 (6.7-8.2)	6.9 (6.5-7.5)	0.0002
eGFR	46 (39-56)	49 (42-58)	0.3321
ACR	267 (153-383)	78 (34-153)	0.0000
SBP	140 (130-156)	134 (122-144)	0.0017
DBP	78 (70-80)	75 (70-80)	0.0048
Potassium	4.4 (4.0-4.6)	4.4 (4.1-4.8)	0.0098

HbA1c: Glycated hemoglobin A1c; eGFR: Estimated glomerular filtration rate; ACR: Albuminuria/creatinuria ratio; SBP: Systolic blood pressure; DBP: Diastolic blood pressure.

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Citation: Arnedo RD, Polo VS, Garcia JB, Gutiérrez JF, Clason ER, Domínguez D, Rebutti GM, Mancia CM, López RT, Meza MR, López DT, Muñoz Zambrano JJ, Herrera EL, Dina-Batlle E, Terrones MC, de Moraes TP, Yánez TR, Osorio W, Cabeza AA, Rico-Fontalvo J. Efficacy and safety of finerenone in diabetic kidney disease: Latin American experience from FINDKDLATAM trial. World J Nephrol 2026; 15(1): 115933
URL: https://www.wjgnet.com/2220-6124/full/v15/i1/115933.htm
DOI: https://dx.doi.org/10.5527/wjn.v15.i1.115933

Arnedo RD, Polo VS, Garcia JB, Gutiérrez JF, Clason ER, Domínguez D, Rebutti GM, Mancia CM, López RT, Meza MR, López DT, Muñoz Zambrano JJ, Herrera EL, Dina-Batlle E, Terrones MC, de Moraes TP, Yánez TR, Osorio W, Cabeza AA, Rico-Fontalvo J. Efficacy and safety of finerenone in diabetic kidney disease: Latin American experience from FINDKDLATAM trial. World J Nephrol 2026; 15(1): 115933 [PMID: 41884241 DOI: 10.5527/wjn.v15.i1.115933]

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