Prognostic value of the MEST-C score in long-term outcomes of immunoglobulin A nephropathy patients: Insights from a developing country

Table 3 Comparison of clinical characteristics at kidney biopsy in correlation with MEST-C scores, n (%)/mean ± SD

	HTN	P value	Proteinuria (g/24 hours)	P value	eGFR (mL/minute/1.73 m2)	P value
Mesangial hypercellularity
M0	15 (42.8)	0.53	2.90 ± 1.78	0.57	63.74 ± 50.09	0.55
M1	29 (34.9)		2.63 ± 2.48		69.56 ± 42.26
Endocapillary hypercellularity
E0	38 (36.5)	0.77	2.46 ± 2.01	0.002	70.61 ± 44.87	0.04
E1	6 (42.8)		4.95 ± 3.37		47.28 ± 37.91
Segmental glomerular sclerosis
S0	21 (31.8)	0.18	2.86 ± 2.85	0.56	65.70 ± 47.36	0.56
S1	23 (44.2)		2.57 ± 1.60		70.46 ± 41.20
IFTA (T)
T0	12 (24)	0.01	2.48 ± 2.24	0.34	92.77 ± 37.34	0.00
T1-T2	32 (47)		2.94 ± 2.33		49.83 ± 40.77
Cellular crescents
C0	31 (40.7)	0.32	2.31 ± 1.96	0.02	81.20 ± 39.56	0.00
C1-C2	13 (30.9)		3.78 ± 2.76		43.92 ± 43.50

HTN: Hypertension; eGFR: Estimated glomerular filtration rate; IFTA: Tubular atrophy/interstitial fibrosis.