Prognostic value of the MEST-C score in long-term outcomes of immunoglobulin A nephropathy patients: Insights from a developing country

Table 2 Biopsy findings of immunoglobulin A nephropathy patients categorized by MEST-C score, n (%)/mean ± SD

	n = 118
Total glomeruli	14.86 ± 7.02
Globally sclerosed	2.99 ± 3.73
Mesangial hypercellularity
M0	35 (29.7)
M1	83 (70.3)
Endocapillary hypercellularity
E0	104 (88.1)
E1	14 (11.9)
Segmental glomerular sclerosis
S0	66 (55.9)
S1	52 (44.1)
IFTA (T)
T0	50 (42.4)
T1	56 (47.5)
T2	12 (10.2)
Cellular crescents
C0	76 (64.4)
C1	27 (22.9)
C2	15 (12.7)
C3 staining on IF
Negative	32 (27.1)
+1	43 (36.4)
+2	38 (32.2)
+3	4 (4.2)
IgA staining on IF
Alone	42 (35.6)
IgA + IgG co-deposition	14 (11.9)
IgA + IgM co-deposition	62 (52.5)
MEST-C score
1	30 (25.4)
2	31 (26.3)
3	35 (29.7)
4	16 (13.6)
5	5 (4.2)
6	1 (0.80)
7	0

IFTA: Tubular atrophy/interstitial fibrosis; C3: Complement component 3; IF: Immunofluorescence; Ig: Immunoglobulin.