Prognostic value of the MEST-C score in long-term outcomes of immunoglobulin A nephropathy patients: Insights from a developing country

Table 1 Baseline demographic and clinical characteristics of patients with immunoglobulin A nephropathy, n (%)/mean ± SD

	n = 118
Age at biopsy (years)	29.03 ± 10.58
Gender
Male	73 (61.9)
Female	45 (38.1)
Weight (kg)	65.62 ± 15.14
HTN	44 (37.3)
Presence of edema	65 (55.1)
Evidence of recent infection	26 (22)
Asymptomatic	24 (20.3)
Urinary abnormality	14 (11.9)
Abnormal creatinine	5 (4.2)
Newly diagnosed HTN	5 (4.2)
Symptomatic	94 (79.7)
Nephrotic syndrome	26 (22)
Nephritic syndrome	45 (38.1)
Gross hematuria	23 (19.49)
Proteinuria (dipstick)
Trace	5 (4.2)
+1	11 (9.3)
+2	25 (21.2)
+3	59 (50)
+4	18 (15.3)
Microscopic hematuria
Trace	11 (9.3)
+1	20 (16.9)
+2	21 (17.8)
+3	52 (44.1)
+4	14 (11.9)
Serum creatinine (mg/dL), median (IQR)	1.4 (0.85-2.45)
eGFR (mL/minute/1.73 m2)	67.82 ± 44.60
Serum albumin (g/dL)	3.19 ± 0.81
Spot PCR (mg/dL) or 24-hour proteinuria (g/24 hours), median (IQR)	2.13 (1.08-3.74)
Spot PCR (mg/dL) or 24-hour proteinuria (g/24 hours)
Proteinuria < 1 g	5 (4.2)
Proteinuria 1-3 g	95 (80.5)
Proteinuria > 3 g	18 (15.3)
Serum C3 levels
Low (< 0.8 g/L)	7 (5.93)
Normal (> 0.8 g/L)	111 (94.06)
Serum C4 levels
Low (< 0.16 g/L)	3 (2.54)
Normal (> 0.16 g/L)	115 (97.45)
Required KRT (%)	43 (26.4)
Antiproteinuric treatment	102 (86.4)
Immunosuppressive treatment	73 (61.9)
Steroid alone	43 (36.4)
Combination treatment	30 (25.4)

HTN: Hypertension; IQR: Interquartile rang; eGFR: Estimated glomerular filtration rate; PCR: Protein-to-creatinine ratio; C: Crescent formation; KRT: Kidney replacement therapy.