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Observational Study
©The Author(s) 2025.
World J Nephrol. Dec 25, 2025; 14(4): 111639
Published online Dec 25, 2025. doi: 10.5527/wjn.v14.i4.111639
Table 6 Prevalence of individual symptoms in the overall study group, n (%)
Symptoms studied
Moderate-severe (3, 4)
Mild (1, 2)
No symptoms (0)
Worrying53 (33.7)68 (43.3)36 (22.9)
Trouble falling asleep45 (28.6)47 (29.9)65 (41.4)
Feeling bad44 (28)69 (43.9)44 (28)
Muscle cramps37 (23.5)59 (37.5)61 (38.8)
Trouble staying asleep41 (26.1)33 (21)83 (52.8)
Dry mouth26 (16.5)50 (31.8)81 (51.5)
Feeling tired/lack of energy21 (13.4)69 (43.9)67 (42.6)
Bone/joint pain19 (12.1)62 (39.4)76 (48.4)
Dry skin17 (10.8)74 (47.1)66 (42)
Itching16 (10.1)42 (26.7)99 (63)
Feeling nervous15 (9.5)46 (29.2)96 (61.1)
Swelling in legs14 (8.9)47 (29.9)96 (61.1)
Cough13 (8.2)53 (33.7)91 (57.9)
Muscle soreness12 (7.6)58 (36.9)87 (55.4)
Headache11 (7)46 (29.2)100 (63.6)
Numbness or tingling in feet11 (7)28 (17.8)118 (75.1)
Difficulty concentration11 (7)57 (36.3)89 (56.6)
Restless legs11 (7)58 (36.9)88 (56)
Feeling irritable11 (7)35 (22.2)111 (70.7)
Decreased interest in sex11 (7)16 (10.2)130 (82.8)
Shortness of breath10 (6)52 (33.1)95 (60.5)
Constipation10 (6)22 (14)125 (79.6)
Decreased appetite9 (5)42 (26.7)106 (67.5)
Chest pain4 (2.5)25 (15.9)128 (81.5)
Vomiting7 (4.4)26 (16.5)124 (78.9)
Nausea7 (4.4)15 (9.5)135 (85.9)
Light-headedness7 (4.4)32 (20.3)118 (75.1)
Difficulty becoming sexually aroused5 (3.1)13 (8.2)139 (88.5)
Diarrhea3 (1.9)12 (7.6)142 (90.4)


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