©The Author(s) 2025.
World J Nephrol. Dec 25, 2025; 14(4): 109767
Published online Dec 25, 2025. doi: 10.5527/wjn.v14.i4.109767
Published online Dec 25, 2025. doi: 10.5527/wjn.v14.i4.109767
Table 5 Three generations of hepatitis B vaccines
| Vaccine generation | Hepatitis B antigen | Examples | Remarks |
| First | SHBs protein | Heptavax-B (Merck & Co., United States); Hevac B (Pasteur, France); KGC (Korea Green Cross, Korea) | Not in use |
| Second | SHBs, MHBs protein | Recombivax (Merck & Co., United States); Engerix-B (GSK, Belgium); TGP 943 [P31] (Takeda, Japan); Fendrix (GSK, Belgium); HBVaxPro (Sanofi-Pasteur, MSD) | Most commonly used and easily available |
| Third | SHBs, MHBs, Large hepatitis B surface protein | GenHevac B (Pasteur, France); Bio-Hep-B (Bio Technology General, Israel) | Limited availability and higher costs |
- Citation: Singh S, Singh R, Kaul A, Goel A. Hepatitis B and chronic kidney disease: Bench to bedside. World J Nephrol 2025; 14(4): 109767
- URL: https://www.wjgnet.com/2220-6124/full/v14/i4/109767.htm
- DOI: https://dx.doi.org/10.5527/wjn.v14.i4.109767