Hepatitis B and chronic kidney disease: Bench to bedside

Table 4 Dose modifications of antiviral drugs recommended according to estimated glomerular filtration rate

Antiviral drug	Creatinine clearance (mL per minute)
	> 50	30-49	10-29	< 10 or dialysis
Tenofovir disoproxil fumarate	300 mg tablet once a day	300 mg tablet every 48 hours	300 mg tablet every 72-96 hours	300 mg tablet every seven days or following completion of dialysis
Entecavir	0.5 mg tablet daily	0.5 mg tablet every 48 hours	0.5 mg tablet every 72 hours	0.5 mg tablet every week
Tenofovir alafenamide	25 mg tablet once a day	25 mg tablet once a day	25 mg tablet once a day up to creatinine clearance of 15 mL/minute	25 mg tablet after completion of dialysis

GFR: Glomerular filtration rate.