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©The Author(s) 2025.
World J Nephrol. Dec 25, 2025; 14(4): 109457
Published online Dec 25, 2025. doi: 10.5527/wjn.v14.i4.109457
Figure 2
Figure 2 Potential kidney-cardiovascular and metabolic effects of semaglutide in people with chronic kidney disease. ANP: Atrial natriuretic peptide; BP: Blood pressure; CKD: Chronic kidney disease; CV: Cardiovascular; HbA1c: Glycated haemoglobin; KIM-1: Kidney injury molecule-1; LDL-C: Low-density lipoprotein cholesterol; NF-κB: Nuclear factor-κB; NHE3: Sodium-hydrogen exchanger-3; NO: Nitric oxide; RAAS: Renin-angiotensin-aldosterone system; RAGE: Receptor for advanced glycation end products; TGF-β: Transforming growth factor-β. Created in BioRender (https://BioRender.com/yd9812v).


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