Relationship of lupus nephritis and pregnancy: A narrative review

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Nephrol. Dec 25, 2024; 13(4): 99700
Published online Dec 25, 2024. doi: 10.5527/wjn.v13.i4.99700

Table 3 Medication compatibility with pregnancy and lactation

Medications	Before conception	During pregnancy	Lactation
Stop at conception
Abatacept	Stop with the positive pregnancy test		+
Belimumab	Stop with the positive pregnancy test		+
Rituximab	Stop with the positive pregnancy test		+
Compatible drugs
Hydroxychloroquine	+	+	+
Azathioprine	+	+	+
Cyclosporine	+	+	+
Tacrolimus	+	+	+
Sulfasalazine	+	+	+
Prednisone	Dose < 20 mg/day	Dose < 20 mg/day	Dose < 20 mg/day
NSAIDs	Discontinue w/difficulty conceiving	Stop at week 20	+
Non-compatible drugs
Cyclophosphamide	Stop 3 months before conception	x	x
MMF/mycophenolic acid	Stop 6 weeks before conception	x	x
Methotrexate	Stop 1-3 months before conception	x	x low transfer into breast milk

NSAIDs: Non-steroidal anti-inflammatory drugs; MMF: Mycophenolate mofetil.

Citation: Elahi T, Ahmed S, Mubarak M. Relationship of lupus nephritis and pregnancy: A narrative review. World J Nephrol 2024; 13(4): 99700
URL: https://www.wjgnet.com/2220-6124/full/v13/i4/99700.htm
DOI: https://dx.doi.org/10.5527/wjn.v13.i4.99700

Elahi T, Ahmed S, Mubarak M. Relationship of lupus nephritis and pregnancy: A narrative review. World J Nephrol 2024; 13(4): 99700 [PMID: 39723351 DOI: 10.5527/wjn.v13.i4.99700]

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