Relationship of lupus nephritis and pregnancy: A narrative review

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Nephrol. Dec 25, 2024; 13(4): 99700
Published online Dec 25, 2024. doi: 10.5527/wjn.v13.i4.99700

Table 2 Lupus nephritis in pregnancy: Evaluation and monitoring

Before pregnancy	Every 6-8 weeks (adjustable)¹
Complete metabolic panel	Complete metabolic panel
Prothrombin time/partial thromboplastin time
24-h urinary protein and creatinine clearance²
sPCR	sPCR
Anti-dsDNA	Anti-dsDNA
Anti-Ro/SS-A and anti-La/SS-B antibodies
Lupus anticoagulant³
Anticardiolipin IgG, IgM, IgA³
Anti-β2 glycoprotein I IgG, IgM, IgA³
Complement levels (C3, C4)	Complement levels (C3, C4)
Uric acid	Uric acid
Urine detailed report with microscopy	Urine detailed report with microscopy

¹Adjust monitoring intervals based on the clinical situation.

²For patients with proteinuria, consider repeating the 24-hour urine test each trimester.

³If the test is positive for the first time, repeat it after 12 weeks.

Anti-dsDNA: anti-double stranded DNA; sPCR: Spot protein/creatinine ratio.

Citation: Elahi T, Ahmed S, Mubarak M. Relationship of lupus nephritis and pregnancy: A narrative review. World J Nephrol 2024; 13(4): 99700
URL: https://www.wjgnet.com/2220-6124/full/v13/i4/99700.htm
DOI: https://dx.doi.org/10.5527/wjn.v13.i4.99700

Elahi T, Ahmed S, Mubarak M. Relationship of lupus nephritis and pregnancy: A narrative review. World J Nephrol 2024; 13(4): 99700 [PMID: 39723351 DOI: 10.5527/wjn.v13.i4.99700]

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