Clinical course and outcome of adult patients with primary focal segmental glomerulosclerosis with kidney function loss on presentation

Table 1 Demographic characteristics, clinical features, biochemical and histopathological results of adult patients of focal segmental glomerulosclerosis with kidney function loss at presentation, n = 98

Parameters	Results
Age in years	30.9 ± 13.6
Sex as male:female	2.5:1
Systolic BP in mmHg	132.7 ± 19.8
Diastolic BP in mmHg	87.4 ± 12.7
Initial proteinuria in mg/24 hours	5945.1 ± 4007.9
Serum albumin in g/dL	2.1 ± 1.0
Serum creatinine in mg/dL	2.2 ± 1.3
Renal insufficiency in males	70 (71.4)
Renal insufficiency in females	28 (28.6)
Estimated glomerular filtration rate on presentation in mL/minute/1.73 m2	37.1 ± 12.8
Histopathological findings
Number of glomeruli	16.4 ± 8.2
Number of glomeruli with global sclerosis	3.4 ± 2.9
Number of glomeruli with segmental sclerosis	3.1 ± 3.0
Tubular atrophy
Mild	41 (41.8)
Moderate	11 (11.2)
Fibrointimal thickening of arteries
Mild	9 (4.2)
Moderate	4 (4.1)
Focal segmental glomerulosclerosis variants
Not otherwise specified	43 (43.9)
Tip	20 (20.4)
Collapsing	19 (19.4)
Hilar	1 (1.0)
Cellular	1 (1.0)
Unknown/unclassified	14 (14.3)

Data are n (%). BP: Blood pressure.