Copyright
©The Author(s) 2024.
World J Nephrol. Mar 25, 2024; 13(1): 88028
Published online Mar 25, 2024. doi: 10.5527/wjn.v13.i1.88028
Published online Mar 25, 2024. doi: 10.5527/wjn.v13.i1.88028
Table 2 Histopathology findings on kidney biopsies in the three most common focal segmental glomerulosclerosis morphologic variants
| Histopathology | All patients (n = 343) | NOS (n = 185) | TIP (n = 100) | COL (n = 58) | P value |
| No. of glomeruli, mean ± SD | 17.3 ± 8.4 | 16.4 ± 8.7 | 18.1 ± 6.8 | 17.3 ± 9.7 | 0.370 |
| No. of glomeruli with global sclerosis, mean ± SD | 2.6 ± 2.2 | 2.1 ± 2.3 | 2.0 ± 0.8 | 3.6 ± 2.5 | 0.001 |
| No. of glomeruli with segmental collapse, mean ± SD | 2.9 ± 2.7 | 2.4 ± 1.8 | 2.6 ± 2.8 | 13.7 ± 3.3 | 0.050 |
| Tubular atrophy, mild, n (%) | 175/201 (87.1) | 91 (52.0) | 49 (28.0) | 35 (20.0) | < 0.001 |
| Tubular atrophy, moderate, n (%) | 26/201 (12.9) | 9 (36.6) | 1 (3.8) | 16(61.5) | |
| Fibrointimal thickening of arteries, mild, n (%) | 25/32 (98.1) | 13 (52.0) | 7 (28.0) | 5 (20.0) | 0.413 |
| Fibrointimal thickening of arteries, moderate, n (%) | 7/32 (21.9) | 5 (27.8) | 2 (22.2) | 0 (0.0) |
- Citation: Jafry NH, Manan S, Rashid R, Mubarak M. Clinicopathological features and medium-term outcomes of histologic variants of primary focal segmental glomerulosclerosis in adults: A retrospective study. World J Nephrol 2024; 13(1): 88028
- URL: https://www.wjgnet.com/2220-6124/full/v13/i1/88028.htm
- DOI: https://dx.doi.org/10.5527/wjn.v13.i1.88028