Prediction of mortality among patients with chronic kidney disease: A systematic review

Table 2 Predictive factors for mortality in chronic kidney disease patients

AUC range	Interpretation	Predictive factors (AUC)	Subjects	Ref.
≥ 0.90	Outstanding	-	-	-
0.80-0.89	Excellent	NT-proBNP (0.83)	HD	Sun et al[22]
		BNP (0.82)	HD	Breidthardt et al[24]
		SuPAR (0.84)	HD	Wlazeł et al[29]
		Augmentation index (0.81)	ND, HD, PD	Mukai et al[32]
		Left atrial reservoir strain (0.84)	ND	Gan et al[35]
		CRP (0.80)	HD, PD	Rroji et al[36]
		Systolic PAP (0.80)	HD, PD	Rroji et al[36]
0.70-0.79	Acceptable	APACHE III (0.76)	HD	Dara et al[19]
		ICED (0.72)	HD, PD	Miskulin et al[20]
		cTnT (0.77)	PD	Wang et al[21],
		NT-proBNP > 10000 pg/mL (0.75)	HD	Sun et al[22]
		MCE perfusion defect (0.75)	HD	Tomaszuk-Kazberuk et al[25]
		DFA1 < 0.95 (0.76)	PD	Chiang et al[26]
		Neutrophil/lymphocyte ratio (0.79)	HD	Sato et al[27]
		UPCR (0.78)	ND	Wang et al[28]
		eGFR (0.75)	ND	Wang et al[28]
		Mitral E/E’ ratio (0.74, 0.75)	ND, HD, PD	Wang et al[28] and Rroji et al[36]
		LV mass index (0.72, 0.76)	ND, HD, PD	Wang et al[28] and Rroji et al[36]
		Mortality risk score (0.79)	ND	Danial et al[30]
		Malnutrition inflammation score (0.71)	ND	Jagadeswaran et al[31]
		Skin autofluorescence (0.78)	ND, HD, PD	Mukai et al[32]
		Rennes score (0.79)	HD, PD	Pladys et al[33]
		Modified CCI (0.70)	HD, PD	Pladys et al[33]
		Pulse pressure (0.72)	HD, PD	Rroji et al[36]

APACHE: Acute physiology and chronic health evaluation; AUC: Area under receiver operating characteristic curve; BMI: Body mass index; BNP: Brain natriuretic peptide; CAPD: Continuous ambulatory peritoneal dialysis; CCI: Charlson Comorbidity Index; CKD: Chronic kidney disease; CRP: C-reactive protein; CI: Confidence interval; cTnT: Cardiac troponin T; CV: Cardiovascular; E/E’: Ratio of early inflow velocity/annular diastolic velocity; eGFR: Estimated glomerular filtration rate; ESRD: End-stage renal disease; HD: Hemodialysis; ICED: Index of coexisting disease; LV: Left ventricular; MCE: Myocardial contrast echocardiography; ND: Non-dialysis; NT-proBNP: N-terminal pro-brain natriuretic peptide; PAP: Pulmonary artery pressure; PD: Peritoneal dialysis; REIN: Renal epidemiology and information network; SOFA: Sequential organ failure assessment; SNDS: French national health insurance information system; SuPAR: Soluble urokinase plasminogen activator receptor; UPCR: Urine protein creatinine ratio.