Pathogenicity of a currently circulating Chinese variant pseudorabies virus in pigs

Figure 3 Hematoxylin and eosin staining of multiple tissues of pigs inoculated with HN1201 (A-G) and Fa strain (H and I). A: Tonsil - tonsillar lymphoid tissue necrosis and formation of large necrotic foci; B: Lung - vascular congestion and hemorrhage (lower arrow), with bronchial epithelial necrosis and necrotic cells within the lumen (upper arrow); C: Brain - lymphocyte infiltration around the small blood vessels in the brain cortex, non-suppurative encephalitis; D: Cerebellum - Purkinje cell degeneration and necrosis; E: Hilar lymph nodes - vascular dilatation and congestion, and lymphatic tissue necrosis; F: Spleen - white pulp structure disappeared and white necrotic marrow lymphocytes formed large necrotic foci; G: Liver - necrotic foci formation; H: Brain - coalescing non-suppurative encephalitis with neuronal degeneration and perivascular cuffing; I: Cerebellum - Purkinje cell degeneration and necrosis.