Study of extended-spectrum beta-lactamases and AmpC beta-lactamases producing Klebsiella from clinical samples in tertiary care hospital of Punjab

doi:10.5501/wjv.v15.i1.118602

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World Journal of Virology

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2220-3249

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Virol. Mar 25, 2026; 15(1): 118602
Published online Mar 25, 2026. doi: 10.5501/wjv.v15.i1.118602

Table 3 Antimicrobial susceptibility patterns of AmpC producers vs non-AmpC producers among Klebsiella isolates, n (%)

Antibiotics	AmpC producers (n = 62)			Non AmpC producers (n = 68)			χ² statistics	P value
Antibiotics	Susceptible	Resistance	Intermediate	Susceptible	Resistance	Intermediate	χ² statistics	P value
Ampicillin	0 (0)	62 (100)	0 (0)	0 (0)	68 (100)	0 (0)	0	1
Amoxicillin	0 (0)	62 (100)	0 (0)	0 (0)	68 (100)	0 (0)	0	1
Amoxicillin-clavulanic acid	7 (11.29)	50 (80.64)	5 (8.06)	25 (36.76)	43 (63.23)	0 (0)	15.41	0.0005^a
Cefotaxime	8 (12.9)	52 (83.87)	2 (3.22)	15 (22.5)	53 (77.94)	0 (0)	3.87	0.14
Ceftazidime	9 (14.51)	53 (85.48)	0 (0)	15 (22.5)	53 (77.94)	0 (0)	1.23	0.54
Ciprofloxacin	4 (6.451)	57 (91.93)	1 (1.61)	11 (16.17)	54 (79.41)	3 (4.41)	4.08	0.13
Gentamicin	37 (59.67)	24 (38.70)	1 (1.61)	44 (64.70)	24 (35.29)	0 (0)	1.33	0.51
Amikacin	27 (43.54)	27 (43.54)	8 (12.9)	34 (50)	31 (45.58)	3 (4.41)	3.08	0.21
Piperacillin-tazobactam	19 (30.64)	39 (62.90)	4 (6.451)	29 (42.64)	31 (45.58)	8 (11.76)	4.06	0.13
Meropenem	23 (37.09)	39 (62.90)	0 (0)	38 (55.88)	30 (44.11)	0 (0)	4.6	0.10
Imipenem	23 (37.09)	38 (61.29)	1 (1.61)	39 (57.35)	29 (42.64)	0 (0)	6.07	0.04^a
Nitrofurantoin¹	3 (17.64)	14 (82.35)	0 (0)	2 (20)	8 (80)	0 (0)	0.02	0.99
Norfloxacin¹	5 (29.41)	12 (70.58)	0 (0)	2 (20)	8 (80)	0 (0)	0.29	0.86

¹Norfloxacin and nitrofurantoin tested for urine specimens only (n = 17 AmpC producers; n = 10 non-AmpC producers).

^aP value means significant.

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Citation: Kaur H, Arora S, Sharma V, Kaur K, Kamboj S. Study of extended-spectrum beta-lactamases and AmpC beta-lactamases producing Klebsiella from clinical samples in tertiary care hospital of Punjab. World J Virol 2026; 15(1): 118602
URL: https://www.wjgnet.com/2220-3249/full/v15/i1/118602.htm
DOI: https://dx.doi.org/10.5501/wjv.v15.i1.118602

Kaur H, Arora S, Sharma V, Kaur K, Kamboj S. Study of extended-spectrum beta-lactamases and AmpC beta-lactamases producing Klebsiella from clinical samples in tertiary care hospital of Punjab. World J Virol 2026; 15(1): 118602 [PMID: 41884455 DOI: 10.5501/wjv.v15.i1.118602]

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