Viral hepatitis after liver transplantation: A brief overview

Table 3 Pros and cons of treatment of hepatitis C virus related decompensated cirrhosis with directly acting antivirals

Pros of treatment	Cons of treatment with directly acting antivirals
Improvement of liver function with survival till LT	Slight improvement in MELD score may not be sufficient enough overall functional improvement
Some patients may get delisted from LT waiting list	Due to lower MELD score patients may not get a liver timely
Only option of treatment for patients not opting for LT	Sustained viral response rate may be lower in patients with decompensated cirrhosis
Reduced rate of recurrence after LT	Some patients may die during therapy
Less risk of recurrent cirrhosis due to hepatitis C virus

LT: Liver transplantation; MELD: Model for end stage liver disease.