Viral hepatitis after liver transplantation: A brief overview

doi:10.5501/wjv.v15.i1.114321

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World Journal of Virology

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2220-3249

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Virol. Mar 25, 2026; 15(1): 114321
Published online Mar 25, 2026. doi: 10.5501/wjv.v15.i1.114321

Table 1 Management of hepatitis B surface antigen positive recipients in setting of liver transplantation

Donor status	Recipient status	Management
HBsAg positive or anti-HBc positive	HBsAg positive	Lifelong antiviral treatment ± hepatitis B immunoglobulin¹
	Anti-HBc positive	Lifelong antiviral treatment
	Anti-HBs titre ≥ 10 mIU/mL	No therapy required
	Anti-HBs titre < 10 mIU/mL	Booster dose and repeat titre after 1 month; Lifelong antiviral treatment if transplanted before achieving protective antibody titre

¹Detectable hepatitis B virus DNA levels at liver transplantation, hepatitis D virus co-infection, hepatocelular carcinoma liver transplantation, drug-resistant hepatitis B virus.

Anti-HBc: Hepatitis B core antibody; HBs: Hepatitis B surface; HBsAg: Hepatitis B surface antigen.

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Citation: Praharaj DL, Giri S, Anand AC, Mallick B, Nath P, Sahu SK, Pattnaik B, Acharya SK, Chawla YK. Viral hepatitis after liver transplantation: A brief overview. World J Virol 2026; 15(1): 114321
URL: https://www.wjgnet.com/2220-3249/full/v15/i1/114321.htm
DOI: https://dx.doi.org/10.5501/wjv.v15.i1.114321

Praharaj DL, Giri S, Anand AC, Mallick B, Nath P, Sahu SK, Pattnaik B, Acharya SK, Chawla YK. Viral hepatitis after liver transplantation: A brief overview. World J Virol 2026; 15(1): 114321 [PMID: 41884460 DOI: 10.5501/wjv.v15.i1.114321]

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