©The Author(s) 2025.
World J Virol. Dec 25, 2025; 14(4): 110435
Published online Dec 25, 2025. doi: 10.5501/wjv.v14.i4.110435
Published online Dec 25, 2025. doi: 10.5501/wjv.v14.i4.110435
Table 2 Clinical presentation of acute hepatitis of unknown etiology in the United Kingdom and United States studies, n (%)
| Symptoms | England (n = 38) | Scotland (n = 32) | United States (n = 16) | |
| Jaundice | Yes | 21 (55.2) | 21 (66) | 13 (81.3) |
| Uknown | 15 (39.5) | 0 (0) | 1 (6.3) | |
| Vomiting | Yes | 20 (52.6) | 22 (69) | 11 (68.8) |
| Uknown | 15 (39.5) | 0 (0) | 5 (31.3) | |
| Diarrhea | Yes | 13 (34.2) | 4 (13% ) | 8 (50.0) |
| Uknown | 15 (39.5) | 0 (0) | 1 (6.3) | |
| Abdominal pain | Yes | 8 (21.0) | 10 (31) | 6 (37.5) |
| Uknown | 15 (39.5) | 0 (0) | 0 (0) | |
| Lethargy | Yes | 8 (21.0) | 10 (31) | 10 (62.5) |
| Uknown | 15 (39.5) | 0 (0) | 1 (6.3) | |
| Pale stool | Yes | 7 (18.4) | NA | NA |
| Uknown | 15 (39.5) | |||
| Cough or coryza | Yes | 5 (13.1) | NA | 5 (31.3) |
| Uknown | 15 (39.5) | 3 (18.8) | ||
| Fever | Yes | 3 (7.9) | NA | 6 (37.5) |
| Uknown | 15 (39.5) | 1 (6.3) | ||
| Poor appetite | Yes | 1 (2.6) | 12 (38) | 10 (62.5) |
| Uknown | 15 (39.5) | 0 (0) | 0 (0) |
- Citation: Komatsu H. Comparison of three pediatric studies investigating acute hepatitis of unknown etiology. World J Virol 2025; 14(4): 110435
- URL: https://www.wjgnet.com/2220-3249/full/v14/i4/110435.htm
- DOI: https://dx.doi.org/10.5501/wjv.v14.i4.110435