OraQuick hepatitis C virus self-test: A new frontier in hepatitis C screening

Table 2 Comparison of the OraQuick hepatitis C virus self-test and other point-of-care tests

Test	Type	Sample	Target	Sensitivity	Specificity	Time	Setting
OraQuick HCV self-test	Rapid Ab	Oral fluid	Anti-HCV Ab	97.8%	100%	20 min	Self-test
Alere Truline HCV rapid test	Rapid Ab	Fingerstick blood	Anti-HCV Ab	99.4%	99.7%	15–20 min	Clinic/POC
SD Bioline HCV test	Rapid Ab	Fingerstick blood	Anti-HCV Ab	99.4%	99.7%	15–20 min	Clinic/POC
GeneXpert HCV Viral Load	NAAT (RT-PCR)	Plasma/serum	HCV RNA	100%	98.5%	Approximately 105 min	Decentralized POC
Lab-based HCV ELISA	ELISA	Serum/plasma	Anti-HCV Ab	≥ 99%	≥ 99%	Hours/days	Central lab
Lab-based HCV RNA (PCR)	RT-PCR (quantitative)	Plasma/serum	HCV RNA	Reference standard	Reference standard	Hours–days	Central lab

HCV: Hepatitis C virus; RT-PCR: Reverse transcription PCR; NAAT: Nucleic acid amplification test; POC: Point of care.