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©The Author(s) 2025.
World J Virol. Sep 25, 2025; 14(3): 103347
Published online Sep 25, 2025. doi: 10.5501/wjv.v14.i3.103347
Table 4 Management of phase 3 of chronic hepatitis B virus infection

APASL[11]
EASL[10]
AASLD[8,9]
INASL[12]
KASL[13]
Biopsy and treatmentBiopsy if ALT 1-2 × ULN or significant fibrosis on non-invasive assessment. Treat if > A2 or ≥ F2Patients with HBeAg (-) disease and family history of HCC or cirrhosis, and extra-hepatic manifestations may be treatedMonitorMonitorMonitor


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