Influence of substance use on rising hepatitis A hospitalizations in the United States: A decade-long comparative study

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Jun 25, 2025 (publication date) through Jun 23, 2025

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World Journal of Virology

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2220-3249

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Virol. Jun 25, 2025; 14(2): 97421
Published online Jun 25, 2025. doi: 10.5501/wjv.v14.i2.97421

Table 1 Demographic characteristics of patients hospitalised for hepatitis A in the United States from 2011-2020, n (%)

Characteristics	Total	No drug use	Active substance use
Number of hospitalizations	55933	40503	15430
Mean age, years (SE)	49.39 (0.09)	53.47 (0.09)	38.68 (0.09)
Age groups, years
18-34	13553 (24.23)	7200 (17.78)	6353 (41.17)
35-49	14616 (26.13)	8541 (21.09)	6075 (39.37)
50-64	14920 (26.67)	12233 (30.20)	2687 (17.41)
65-79	9736 (17.41)	9426 (23.27	310 (2.01)
≥ 80	3108 (5.56)	3103 (7.66)	5 (0.03)
Gender
Male	30805 (55.09)	21072 (52.05)	9733 (63.08)
Female	25109 (44.91)	19412 (47.95)	5697 (36.92)
Race
White	40359 (74.68)	27701 (71.00)	12658 (84.27)
Black	4798 (8.88)	3680 (9.43)	1118 (7.44)
Hispanic	5480 (10.14)	4704 (12.06)	776 (5.17)
Asian or Pacific Islander	1241 (2.30)	1200 (3.08)	41 (0.27)
Native Americans	2161 (4.00)	1733 (4.44)	428 (2.85)
Hospital region
Northeast	8602 (15.38)	6944 (17.14	1658 (10.75)
Midwest	10371 (18.54)	7474 (18.45)	2897 (18.78)
South	28701 (51.31)	19527 (48.21)	9174 (59.46)
West	8259 (14.77)	6558 (16.19)	1701 (11.02
Hospital location and teaching status
Rural	5514 (9.87)	3959 (9.79)	1555 (10.08)
Urban non-teaching	12813 (22.93)	9822 (24.28)	2991 (19.39)
Urban teaching	37548 (67.20)	26668 (65.93)	10880 (70.53)
Discharge against medical advice	2882 (5.20)	1003 (2.50)	1879 (12.27)

Citation: Jahagirdar V, Gautam M, Rasheed W, Blaney H, Ali H, Ghoz H. Influence of substance use on rising hepatitis A hospitalizations in the United States: A decade-long comparative study. World J Virol 2025; 14(2): 97421
URL: https://www.wjgnet.com/2220-3249/full/v14/i2/97421.htm
DOI: https://dx.doi.org/10.5501/wjv.v14.i2.97421