Micro RNAs as a potential biomarker for predicting liver fibrosis severity in hepatitis C virus affected patients

Table 4 Area under the curve, Sensitivity, specificity and Youden index for upregulated miRNAs

HCV groups	Micro RNAs	AUC	Sensitivity	Specificity	Youden Index
Mild	miR-122	0.646	79.5%	40.8%	0.203
	miR-155	0.607	70.2%	44.9%	0.151
	miR-21	0.518	98%	24.5%	0.225
Moderate	miR-122	0.774	92%	62.9%	0.549
	miR-155	0.898	96%	76%	0.720
	miR-21	0.826	96%	72.6%	0.686
Severe	miR-122	0.979	96.2%	89.1%	0.852
	miR-155	0.896	88.5%	79.9%	0.683
	miR-21	0.969	92.3%	87.9%	0.802

AUC: Area under the curve; HCV: Hepatitis C virus.