Dengue induced acute liver failure: A meta summary of case reports

Table 3 Baseline laboratory parameters and hospital course

Parameter of interest	Frequency (%)
Hematocrit, median	42.60 (IQR 15.15)
Total leucocyte count (per µL), median	5800 (IQR 5800)
Platelet count (per µL), median	25500 (IQR 28250)
AST (U/L), median	4625 (IQR 11902.5)
ALT (U/L), median	3100 (IQR 2607)
AST/ALT ratio, median	2.45 (IQR 1.75)
Alkaline phosphatase (IU/L), median	191 (IQR 117)
Total bilirubin (mg/dL), median	5.5 (IQR 5.63)
Direct bilirubin (mg/dL), median	2.55 (IQR 2.75)
INR, median	2.13 (IQR 1.79)
Albumin (g/L), median	2.85 (IQR 0.48)
Creatinine (mg/dL), median	1.63 (IQR 2.12)
MELD score, median	27.5 (IQR 5)
Days of ICU stay, median	6 (IQR 2)
Specific therapies
N-acetyl cysteine	6 (31.6)
Types of organ support
Vasopressors	8 (42.1)
Renal replacement therapy	6 (31.6)
Ventilation	6 (31.6)
MARS	1 (5.3)
Organ failure	14 (73.7)
Neurological	10 (52.6)
Cardiac	8 (42.1)
Renal	7 (36.8)
Respiratory
Complications
Hepatic encephalopathy	13 (68.4)
Bleedings	3 (15.8)
DVT	1 (5.3)
Liver transplantation	2 (10.5)
Death	1 (5.3)

AST: Aspartate aminotransferase; ALT: Alanine transaminase; MARS: Molecular adsorbent recirculating system; ICU: Intensive care unit; DVT: Deep venous thrombosis; MELD: Model for end-stage liver disease.