Review
Copyright ©2012 Baishideng Publishing Group Co.
World J Virol . Feb 12, 2012; 1(1): 31-43
Published online Feb 12, 2012. doi: 10.5501/wjv.v1.i1.31
Table 5 Additional tests in the case of an isolated viral capsid antigen IgG pattern
TestsAdvantagesDisadvantages
EBV IgG immunoblottingUseful in distinguishing acute from past infectionIndividual antibody production; expensive
IgG avidityUseful in distinguishing acute from past infectionIndividual maturation. Not useful in newborns
Molecular biologyUseful in distinguishing acute from past infectionUncorrected conservation of blood sample, presence of nucleasis; expensive; organisational problems
Heterophile antibodiesUseful in distinguishing acute from past infection if positive; inexpensive and simpleNot very sensitive (especially in children)
Anti-EA(D) IgGOf some use in distinguishing acute from past infection; costs the same as a screening testNot useful in at least 10% of cases