Porcine reproductive and respiratory syndrome virus vaccines: Immunogenicity, efficacy and safety aspects

Table 2 Recommendation and vaccination schedule of commercial PRRS modified-live virus vaccines

Vaccine1	Pigs2	Route	Dose (mL)	Program
Ingelvac PRRS MLV	Gilt/Sow	im	2	At any stage of production3
	Piglet/Nursery/Growing	im	2	At any stage of production3
ReproCyc PRRS-PLE	Gilt/Sow	im	5	Primary: 4-6 wk prior to breeding
				Booster: prior to subsequent breeding
Ingelvac PRRS ATP	Nursery/Growing	im	2	At 3-18 wk of age
Porcilis PRRS	Gilt/Sow	im/id	2/0.2	Primary: 2-4 wk prior to breeding
				Booster: 2-4 wk prior to subsequent breeding/or every 4 mo
				At 2 wk of age or older
	Piglet/Nursery/Growing	im/id	2/0.2
Amervac-PRRS	Nursery/Growing	im	2	At 4 wk of age or older
Pyrsvac-183	Gilt/Sow	im	2	Primary: 2-4 wk prior to breeding
				Booster: 3-4 wk prior to subsequent breeding
	Piglet/Nursery/Growing	im	2	At 2-3 wk of age or older

¹Not recommended for use in porcine reproductive and respiratory syndrome virus-negative farms;

²Not recommended for use in boars due to negative impact on semen quality[73];

³Recommended to revaccinate every 3-4 mo for whole herd vaccination program. im: Intramuscularly; id: Intradermally.