Elevated homocysteine levels in human immunodeficiency virus-infected patients under antiretroviral therapy: A meta-analysis

Figure 1 PRISMA flow diagram of the study selection process. After careful discussion between the 3 reviewers, two outcomes were identified and included in the meta-analysis. HIV: Human immunodeficiency virus; ART: Antiretroviral therapy.

Figure 2 Meta-analysis of blood homocysteine concentration in human immunodeficiency virus-infected subjects compared with healthy controls. Calculation based on random effects model. Results are expressed as weighted mean difference of homocysteine (µmol/L) and 95%CI. HIV: Human immunodeficiency virus.

Figure 3 Meta-analysis of serum folate and vitamin B12 levels in human immunodeficiency virus-infected subjects compared with healthy controls. Calculation based on random effects model. Results are expressed as weighted mean difference of folate (pg/mL) and vitamin B12 (pg/mL) and 95%CI.

Figure 4 Meta-analysis of blood homocysteine concentration in human immunodeficiency virus-infected exposed and non-exposed to antiretroviral therapy. Calculation based on random effects model. Results are expressed as weighted mean difference of homocysteine (µmol/L) and 95%CI. ART: Antiretroviral therapy.