Biomarkers in renal transplantation: An updated review

Table 7 Eleven genes overexpressed in the common rejection module[103]

Symbol	Gene name	Cytoband
BASP1	Brain abundant membrane attached signal protein 1	5p15.1
CD6	CD6 molecule	11q12.2
CXCL10	C-X-C Motif chemokine ligand 10	4q21.1
CXCL9	C-X-C Motif chemokine ligand 9	4q21.1
INPP5D	Inositol polyphosphate-5-phosphatase D	2q37.1
ISG20	Interferon stimulated exonuclease gene 20	15q26.1
LCK	LCK protooncogene, SRC family tyrosine kinase	1p35.2
NKG7	Natural killer cell granule protein 7	19q13.41
PSMB9	Proteasome subunit beta 9	6p21.32
RUNX3	Runt related transcription factor 3	1p36.11
TAP1	Transporter 1, ATP binding cassette subfamily B member	6p21.32

These genes were overexpressed in acute rejection across all transplanted organs and could diagnose acute rejection with high specificity and sensitivity.