Acute antibody-mediated rejection after intestinal transplantation

Table 2 Characteristics of 18 patients with diagnosis of acute antibody-medicated rejection

Case	Tx type	POD (d)	XM		DSA at time of Tx and/or rejection	De novo DSA	Vascular alterations	C4d	#ACR ≤360 d
			T-cell	B-cell
1	MV + K	4	1:32	1:16	A1, A25, B8, B18	DR51	++	Focal	0
2	SB	5	1:256	1:512	B7, B44, BW4, DQ1, DR10	DR15, DR51	+++	Diffuse	2
3	SB	5	1:2	1:2	B60	DR16	++	Diffuse	3
41	SB	6	1:8	1:8	B35, B60	A31, DQ7, DR11	+++	Diffuse	0
		109			A24, B604	DR14, DR52	++	Diffuse
5	SB	7	Neg	1:1	A3, B18, DR17	None	++	Diffuse	0
6	MV	7	Neg	1:8	A26, B70, DR52	None	++	Diffuse	1
7	MMV	9	1:32	1:8	A2	None	+++	Diffuse	4
8	SB	10	Neg	Neg	DR52	None	++	Diffuse	1
9	MMV	10	1:2	1:2	B13, BW4, DR7, DR53	DQ1	++	Diffuse	2
101	SB + K	11	Neg	1:4	A32, B8	A1, DR17	++	Diffuse	4
		52			A32, DQ44		++	Diffuse
11	SB + P	14	Neg	1:4	A3, B64	DQ7	++	Diffuse	0
121	SB	15	Neg	Neg	A2, B50	DQ8, DR53, DR4	+	Diffuse	5
		112			B7, B504		+	Focal
13	SB	41	1:256	1:8	A3, BW4, B53	DR18	+++	Diffuse	2
14	MMV	84	1:4	1:1	A25, B14, B18	None	++	Diffuse	1
15	SB	140	Neg	Neg	A24	A28, B78, A30, DQ7, 9	+	Diffuse	1
16	SB	162	1:2	1:2	A24, B444	DQ1, CW5	++	Diffuse	2
172	SB	4	Neg	Neg	A28, B78, A30, DQ7, 9	B44, B58, DR4	+++	Diffuse	2
183	MMV	18	1:1	1:8	A11, B7, DR12, DR17, DQ2	None	++	Diffuse	1

Type of transplant: SB: An isolated small bowel; MMV: A modified multivisceral graft; MV: A full multivisceral graft; P: Pancreas; K: Kidney.

¹Patients with repeat ABMR;

²Patient with a history of ABMR after prior transplant;

³Patient with prior transplant;

⁴DSA detected at time of rejection. POD: ABMR days post-transplant; XM: Cross-match; DSA: Donor-specific antibody; ACR: Acute cellular rejection.