Acute antibody-mediated rejection after intestinal transplantation

Table 1 Donor and recipient demographic and clinical characteristics

Characteristic	Transplants (n = 175)
Donor characteristics
Age (yr)	25.4 ± 9.9
Gender (% male)	77.7
Nonwhite race (%)	16.6
Cold ischemic time (h)	7.6 ± 1.5
Recipient characteristics
Age at transplantation (yr)	43.0 ± 12.5
Gender (% male)	38.9
Nonwhite race (%)	5.9
Primary diagnoses, n (%)
Vascular occlusion	59 (33.7)
Crohn’s disease	34 (19.4)
Neoplastic disorders	28 (16.0)
Motility disorders	21 (12.0)
Others	33 (18.9)
Donor/recipient sex mismatches (%)	56.6
Donor CMV positive/recipient negative (%)	21.9
Type of graft liver-free/liver-inclusive (%)	61.1/38.9
Two mismatches in HLA loci A/B/DR (%)	39.1/82.1/66.9
PRA at transplantation (≥ 10%) Class I (%)	40
Class II (%)	26.3
Positive T/B cell cross-match (%)	25.7
Preformed DSA (%)	30.3
Retransplantation (%)	6.7
Induction, n (%)
None	41 (23.4)
Zenapax	3 (1.7)
Thymoglobulin	7 (4.0)
Campath-1H	124 (70.9)
Follow-up (mo; range)	37.5 ± 22.7 (0.7 to 81.5)

CMV: Cytomegalovirus; PRA: Panel reactive antibody; HLA: Human leukocyte antigens; DSA: Donor-specific antibody.