Editorial
Copyright ©2013 Baishideng Publishing Group Co.
World J Transplant. Dec 24, 2013; 3(4): 48-53
Published online Dec 24, 2013. doi: 10.5500/wjt.v3.i4.48
Table 1 Summary of current open clinical trials with interventions in islet transplantation (Adapted from Clinical Trials.gov)
Trial IDDescriptionInstitution
NCT01653899Caspase Inhibition in Islet TransplantationUniversity of Alberta
NCT00468117Efficacy of Islet After Kidney TransplantationNational Institute of Allergy and Infectious Diseases
NCT01705899Islet Allotransplantation in Type 1 DiabetesOhio State University
NCT01652911A Phase I/II Study of the Safety and Efficacy of Sernova's Cell PouchTM for Therapeutic Islet TransplantationUniversity of Alberta
NCT00784966Islet After Kidney Transplant for Type 1 DiabetesVirginia Commonwealth University
NCT00790257Safety and Efficacy Study of Encapsulated Human Islets Allotransplantation to Treat Type 1 DiabetesCliniques universitaires Saint-Luc-Université Catholique de Louvain
NCT00853944Effect of Sitagliptin on Graft Function Following Islet TransplantationUniversity of British Columbia
NCT00249652Transplant and Addiction Project 1National Institute on Drug Abuse
NCT00530686Pancreatic Islet Cell Transplantation - A Novel Approach to Improve Islet Quality and EngraftmentBaylor Research Institute
NCT01123187Islet Cell Transplantation in Patients With Type 1 Diabetes With Previous Kidney TransplantationUniversity Hospital, Lille
NCT01817959Study to Assess Efficacy and Safety of Reparixin in Pancreatic Islet TransplantationDompé s.p.a.
NCT00679042Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at Chicago ProtocolUniversity of Illinois
NCT00453817Islet of Langerhans Graft Monitoring by Magnetic Resonance ImagingUniversity Hospital, Geneva
NCT00853424A Comparison of Islet Cell Transplantation With Medical Therapy for the Treatment of Diabetic Eye DiseaseUniversity of British Columbia
NCT00789308Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet TransplantationNational Institute of Allergy and Infectious Diseases
NCT01148680Trial Comparing Metabolic Efficiency of Islet Graft to Intensive Insulin Therapy for Type 1 Diabetes’s TreatmentUniversity Hospital, Grenoble
NCT01241864Islet Transplantation in Type 1 Diabetic Kidney AllograftUniversity of Chicago
NCT01722682Bone Marrow vs Liver as Site for Islet TransplantationOspedale San Raffaele
NCT01630850Islet Transplantation in Patients With\Brittle\“Type 1 Diabetes”University of Chicago
NCT01186562Sitagliptin Therapy to Improve Outcomes After Islet AutotransplantUniversity of Minnesota
NCT01285934A Trial of High Dose Immunosuppression and Autologous Hematopoietic Stem Cell Support Versus Intensive Insulin Therapy in Adults With Early Onset T1DMUniversity of Sao Paulo General Hospital
NCT00646724Cotransplantation of Islet and Mesenchymal Stem Cell in Type 1 Diabetic PatientsFuzhou General Hospital
NCT01379729Bet Cell Therapy in Diabetes Type 1AZ-VUB
NCT01341899Efficacy and Safety Study of Autologous Hematopoietic Stem Cell Transplantation to Treat New Onset Type 1 DiabetesThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
NCT01736228Open-label Investigation of the Safety and Efficacy of DIABECELL in Patients With T1DMLiving Cell Technologies
NCT01346098Islet Autotransplantation in Patients at Very High-risk Pancreatic AnastomosisOspedale San Raffaele
NCT00989547Cord Blood Infusion for T1DMTechnische Universität München
NCT00807651Autologous Hematopoietic Stem Cell Transplantation for Early Onset Type 1 DiabetesShanghai Jiao Tong University School of Medicine
NCT01042301Profiling of Original Cellular and Humoral Biomarkers of Type 1 DiabetesNantes University Hospital
NCT01350219Stem Cell Educator Therapy in Type 1 DiabetesTianhe Stem Cell Biotechnologies Inc.
NCT00014911Immunosuppressive Medications for Participants in ITN005CTNational Institute of Allergy and Infectious Diseases