Is it time to give up with calcineurin inhibitors in kidney transplantation?

Table 6 Immunosuppression regimens in alemtuzumab minimization trials

Ref.	Study group			Control group
	Induction	Maintenance		Induction	Maintenance
Chan et al[59]	Alem	TAC, Ster	82	Dac	TAC, MMF, Ster	41
Hanaway et al[60]	Alem	TAC, MMF, Ster	164 70	Bas rATG	TAC, MMF, Ster TAC, MMF, Ster	171 69
Ciancio et al[61]	Alem	TAC, MMF	13	Dac rATG	TAC, MMF, Ster TAC, MMF, Ster	12 13
Ciancio et al[62]	Alem	TAC, MMF, Ster	30	Dac rATG	TAC, MMF, Ster TAC, MMF, Ster	30 30
Farney et al[63]	Alem	TAC/CsA, MMF, Ster	85	rATG	TAC/CsA, MMF, Ster	95
Vathsala et al[64]	Alem	CsA, Ster	20	None	CsA, AZA, Ster	10

Alem: Alemtuzumab; TAC: Tacrolimus; Ster: Steroids; MMF: Mycophenolate mofetil; CsA: Cyclosporine; Dac: Daclizumab; Bas: Basiliximab; rATG: Rabbit antithymocyte globulin.