©2012 Baishideng.
World J Transplant. Aug 24, 2012; 2(4): 51-68
Published online Aug 24, 2012. doi: 10.5500/wjt.v2.i4.51
Published online Aug 24, 2012. doi: 10.5500/wjt.v2.i4.51
Table 4 Comparative adverse effects of prolonged release Tacrolimus and Tacrolimus (%)
| ADR | Prolonged released Tacrolimus | Tacrolimus twice daily |
| Gastrointestinal | ||
| Diarrhea | 45.3 | 44.3 |
| Loose stools | 5.1 | 7.1 |
| Metabolism and nutritional | ||
| Hyperlipidemia | 16.4 | 17.5 |
| Diabetes mellitus | 14.0 | 11.3 |
| Hyponatremia | 2.8 | 0.9 |
| Infections and infestations | ||
| Sinusitis | 7.0 | 3.3 |
| Gastroenteritis | 6.5 | 0.5 |
| Peripheral edema | 35.5 | 34.9 |
| Nervous system | ||
| Tremor | 35.0 | 34.4 |
| Paraesthesia | 5.6 | 1.4 |
| Vascular | ||
| Orthostatasis | 7.0 | 4.7 |
| Lymphocele | 0.5 | 0.9 |
| Psychiatric | ||
| Insomnia | 25.7 | 30.2 |
| Skin | ||
| Alopecia | 6.5 | 7.1 |
- Citation: Kalluri HV, Hardinger KL. Current state of renal transplant immunosuppression: Present and future. World J Transplant 2012; 2(4): 51-68
- URL: https://www.wjgnet.com/2220-3230/full/v2/i4/51.htm
- DOI: https://dx.doi.org/10.5500/wjt.v2.i4.51