Pathophysiological mechanisms of cell death affecting graft survival in liver transplantation

doi:10.5500/wjt.124992

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World Journal of Transplantation

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2220-3230

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Transplant. Sep 18, 2026; 16(3): 124992
Published online Sep 18, 2026. doi: 10.5500/wjt.124992

Table 2 Model for end-stage liver disease score and need for transplantation

Variables	Calculation score equation	Score clinical relevance
TBIL	MELD: (3.78 × TBIL) + (11.2 × INR) + (9.57 × Cr) + 6.43	15 → transplanta-tion
INR	MELD-Na: MELD + 1.32 × (137-Na)-[0.033 × MELD × (137-Na)]	15-24 → interme-diate priority
Cr (mg/dL)		≥ 25 → high priority
Na		≥ 30 → high risk patient

MELD: Model for end-stage liver disease; TBIL: Total bilirubin; INR: International normalized ratio; Cr: Creatinine; Na: Sodium.

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Citation: Mouratidou C, Pavlidis ET, Katsanos G, Kofinas A, Marneri AG, Stavrati KE, Tsoulfas G, Pavlidis TE. Pathophysiological mechanisms of cell death affecting graft survival in liver transplantation. World J Transplant 2026; 16(3): 124992
URL: https://www.wjgnet.com/2220-3230/full/v16/i3/124992.htm
DOI: https://dx.doi.org/10.5500/wjt.124992

Mouratidou C, Pavlidis ET, Katsanos G, Kofinas A, Marneri AG, Stavrati KE, Tsoulfas G, Pavlidis TE. Pathophysiological mechanisms of cell death affecting graft survival in liver transplantation. World J Transplant 2026; 16(3): 124992 [DOI: 10.5500/wjt.124992]

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