Impact of pretransplant donor-specific antibodies and human leukocyte antigen mismatches on graft and patient outcomes: A cohort from Saudi Arabia

doi:10.5500/wjt.122485

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World Journal of Transplantation

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2220-3230

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Transplant. Sep 18, 2026; 16(3): 122485
Published online Sep 18, 2026. doi: 10.5500/wjt.122485

Table 3 Multivariable logistic regression for factors associated with donor-specific antibody positivity

Predictor	OR	95%CI	P value	Significance
Recipient age	1.02	1.01-1.04	0.009	Significant
HLA mismatches	1.31	1.18-1.44	0.0000	Significant
eGFR < 60 at 4 months	1.70	0.82-3.54	0.156	Not significant
Any sensitizing event	0.68	0.26-1.82	0.448	Not significant

eGFR: Estimated glomerular filtration rate; HLA: Human leukocyte antigen; OR: Odds ratio.

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Citation: Al-Qurashi SH, Khalil MAM, Mahmood HHK, Altom AA, Alqurashi YF, Alsaedi ZA, Cruz AJD, Alsharif MM, Bawayan RM, Housawi AA, Sadagah NM. Impact of pretransplant donor-specific antibodies and human leukocyte antigen mismatches on graft and patient outcomes: A cohort from Saudi Arabia. World J Transplant 2026; 16(3): 122485
URL: https://www.wjgnet.com/2220-3230/full/v16/i3/122485.htm
DOI: https://dx.doi.org/10.5500/wjt.122485

Al-Qurashi SH, Khalil MAM, Mahmood HHK, Altom AA, Alqurashi YF, Alsaedi ZA, Cruz AJD, Alsharif MM, Bawayan RM, Housawi AA, Sadagah NM. Impact of pretransplant donor-specific antibodies and human leukocyte antigen mismatches on graft and patient outcomes: A cohort from Saudi Arabia. World J Transplant 2026; 16(3): 122485 [DOI: 10.5500/wjt.122485]

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