Kidney transplant outcomes in patients with complement dysregulation

doi:10.5500/wjt.120969

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World Journal of Transplantation

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2220-3230

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Transplant. Sep 18, 2026; 16(3): 120969
Published online Sep 18, 2026. doi: 10.5500/wjt.120969

Table 4 Distribution of complement genetic abnormalities according to anti-factor H antibody status

Complement genetic abnormality	AFH-positive (n = 15)	AFH-negative (n = 23)	Total n (%)
CFHR1/CFHR3 rearrangements	9	21	30 (78.9)
Duplication	6	13	19
Heterozygous deletion	2	6	8
Homozygous deletion	1	2	3
CFH mutation	3	4	7 (18.4)
Heterozygous mutation	2	3	5
Homozygous mutation	1	1	2
CFHR5 mutation	1	1	2 (5.3)
CFB mutation	1	1	2 (5.3)
No genetic abnormality identified	4	0	4 (10.5)

AFH: Anti-factor H; CFB: Complement factor B; CFH: Complement factor H; CFHR: Complement factor H-related genes.

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Citation: Balwani M, Pasari A, Kashiv P, Ramteke V, Tolani P, Manuja N, Kurundwadkar M, Dubey S, Pawar T, Malde S, Gupta S, Sejpal K, Jeyachandran V, Kute VB. Kidney transplant outcomes in patients with complement dysregulation. World J Transplant 2026; 16(3): 120969
URL: https://www.wjgnet.com/2220-3230/full/v16/i3/120969.htm
DOI: https://dx.doi.org/10.5500/wjt.120969

Balwani M, Pasari A, Kashiv P, Ramteke V, Tolani P, Manuja N, Kurundwadkar M, Dubey S, Pawar T, Malde S, Gupta S, Sejpal K, Jeyachandran V, Kute VB. Kidney transplant outcomes in patients with complement dysregulation. World J Transplant 2026; 16(3): 120969 [DOI: 10.5500/wjt.120969]

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