Phase-specific intraoperative glycemic control in simultaneous pancreas-kidney transplantation

doi:10.5500/wjt.v16.i2.119146

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World Journal of Transplantation

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2220-3230

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Transplant. Jun 18, 2026; 16(2): 119146
Published online Jun 18, 2026. doi: 10.5500/wjt.v16.i2.119146

Table 1 Biological pathways linking intraoperative glycemic variability to early pancreas graft complications[5,22-25,27-40]

Domain	Pathophysiologic effect	Clinical consequence
Endothelium	Oxidative stress, nitric oxide disruption	Microvascular injury
Coagulation	Platelet activation, procoagulant signaling	Graft thrombosis
Innate immunity	Impaired neutrophil function	Infection
β-cell adaptation	Insulin hypersecretion followed by instability	Hypoglycemia

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Citation: Kashiv P, Balwani MR, Tolani P, Pasari A, Saxena K, Kute VB. Phase-specific intraoperative glycemic control in simultaneous pancreas-kidney transplantation. World J Transplant 2026; 16(2): 119146
URL: https://www.wjgnet.com/2220-3230/full/v16/i2/119146.htm
DOI: https://dx.doi.org/10.5500/wjt.v16.i2.119146

Kashiv P, Balwani MR, Tolani P, Pasari A, Saxena K, Kute VB. Phase-specific intraoperative glycemic control in simultaneous pancreas-kidney transplantation. World J Transplant 2026; 16(2): 119146 [PMID: 42281877 DOI: 10.5500/wjt.v16.i2.119146]

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