Thromboelastographic description of intraoperative coagulopathy in patients undergoing liver transplant surgery: A single-center observational study

doi:10.5500/wjt.v16.i2.118880

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 16, Issue 2

This Article

(26)

(21)

(0)

(43)

(445)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Transplantation

ISSN

2220-3230

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Transplant. Jun 18, 2026; 16(2): 118880
Published online Jun 18, 2026. doi: 10.5500/wjt.v16.i2.118880

Table 2 Distribution of coagulation measures by thromboelastography across 4 phases of liver transplant surgery, n (%)

TEG parameters and levels	Distribution of TEG levels across liver transplant surgical phases
TEG parameters and levels	Pre-anhepatic	Anhepatic	Post-reperfusion	End of surgery
Clot initiation time
CK R (TEG 6s)	n = 116	n = 100	n = 116	n = 113
Shortened/Low	19 (16.4)	22 (22.0)	22 (19.0)	12 (10.6)
Normal	87 (75.0)	46 (46.0)	54 (55.2)	85 (75.2)
Prolonged/high	10 (8.6)	32 (32.0)	30 (25.9)	16 (14.2)
R (TEG 5000)	n = 214	n = 175	n = 206	n = 207
Shortened/Low	148 (69.2)	150 (85.7)	93 (45.1)	116 (56.0)
Normal	64 (29.9)	23 (13.1)	94 (45.6)	84 (40.6)
Prolonged/high	2 (0.9)	2 (1.1)	19 (9.2)	7 (3.4)
Clot formation
CFF MA (TEG 6s)	n = 112	n = 94	n = 116	n = 113
Shortened/Low	40 (35.7)	49 (52.1)	53 (45.7)	55 (48.7)
Normal	62 (55.4)	38 (40.4)	60 (51.7)	57 (50.4)
Prolonged/high	10 (8.9)	7 (7.4)	3 (2.6)	1 (0.9)
CFF FLEV (TEG 6s)	n = 46	n = 46	n = 76	n = 62
Shortened/Low	18 (39.1)	25 (54.3)	39 (51.3)	36 (58.1)
Normal	26 (56.5)	20 (43.5)	35 (46.1)	26 (41.9)
Prolonged/high	2 (4.3)	1 (2.2)	2 (2.6)	ND
K (TEG 5000)	n = 212	n = 175	n = 199	n = 203
Shortened/Low	147 (69.3)	123 (70.3)	80 (40.2)	105 (51.7)
Normal	60 (28.3)	44 (25.1)	80 (40.2)	84 (41.4)
Prolonged/high	5 (2.4)	8 (4.6)	39 (19.6)	14 (6.9)
α-angle (TEG 5000)	n = 214	n = 175	n = 205	n = 205
Shortened/Low	4 (1.9)	5 (2.9)	35 (17.1)	10 (4.9)
Normal	37 (17.3)	28 (16.0)	48 (23.4)	43 (21.0)
Prolonged/high	173 (80.8)	142 (81.1)	122 (59.5)	152 (74.1)
Fibrinolysis
CK LY30 (TEG 6s)	n = 78	n = 58	n = 78	n = 74
Normal	69 (88.5)	43 (74.1)	67 (85.9)	73 (98.6)
Prolonged/high	9 (11.5)	15 (25.9)	11 (14.1)	1 (1.4)
LY30 (TEG 5000)	n = 213	n = 175	n = 204	n = 204
Normal	176 (82.6)	118 (67.4)	161 (78.9)	185 (90.7)
Prolonged/high	37 (17.4)	57 (32.6)	43 (21.1)	19 (9.3)
Platelet contribution to clot strength
CRT MA (TEG 6s)	n = 113	n = 93	n = 114	n = 104
Shortened/Low	61 (54.0)	60 (64.5)	80 (70.2)	73 (70.2)
Normal	51 (45.1)	33 (35.5)	34 (29.8)	31 (29.8)
Prolonged/high	1 (0.9)	ND	ND	ND
MA (TEG 5000)	n = 213	n = 175	n = 204	n = 204
Shortened/Low	92 (43.2)	65 (37.1)	138 (67.6)	109 (53.4)
Normal	106 (49.8)	96 (54.9)	64 (31.4)	92 (45.1)
Prolonged/high	15 (7.0)	14 (8.0)	2 (1.0)	3 (1.5)

TEG: Thromboelastography; CK: Citrated kaolin; R: Reaction time; CFF: Citrated functional fibrinogen; MA: Maximum amplitude; FLEV: Functional fibrinogen level; K: Kinetics time; LY30: Percent clot lysis at 30 minutes post-maximum amplitude; CRT: Citrated rapid thromboelastography; ND: No data.

Full Size Table

Citation: Maroun W, Osborn ZF, Garg P, Angappan S, El-Bashir J, Heppell O, Soetedjo J, Pillai S, Miyake K, Mohamed A, Nagai S, Guerra-Londono CE. Thromboelastographic description of intraoperative coagulopathy in patients undergoing liver transplant surgery: A single-center observational study. World J Transplant 2026; 16(2): 118880
URL: https://www.wjgnet.com/2220-3230/full/v16/i2/118880.htm
DOI: https://dx.doi.org/10.5500/wjt.v16.i2.118880

Maroun W, Osborn ZF, Garg P, Angappan S, El-Bashir J, Heppell O, Soetedjo J, Pillai S, Miyake K, Mohamed A, Nagai S, Guerra-Londono CE. Thromboelastographic description of intraoperative coagulopathy in patients undergoing liver transplant surgery: A single-center observational study. World J Transplant 2026; 16(2): 118880 [PMID: 42281870 DOI: 10.5500/wjt.v16.i2.118880]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.