Thromboelastographic description of intraoperative coagulopathy in patients undergoing liver transplant surgery: A single-center observational study

Table 1 Demographic, clinical characteristics and postoperative variables of patients undergoing liver transplant surgery, mean ± SD/n (%)

Characteristic	Result (n = 364)
Age at OLT, years	56.7 ± 10.6
Sex
Female	123 (33.8)
Male	241 (66.2)
Race
Asian	5 (1.4)
Black	24 (6.6)
White	271 (74.5)
Other	64 (17.5)
Body mass index, kg/m2	29.1 ± 5.9
MELD-Na score pre-surgery	22.2 ± 8.7
Blood type
A	147 (40.4)
AB	22 (6.0)
B	49 (13.5)
O	144 (39.6)
Unknown	2 (0.5)
Comorbidities
Chronic pulmonary disease	32 (8.8)
Diabetes	102 (28.0)
End-stage renal disease	10 (2.7)
Hypertension	171(47.0)
Cause of liver failure
Autoimmune hepatitis	16 (4.4)
Alcohol-related	166 (46.6)
Cholangiocarcinoma	5 (1.4)
Cryptogenic	14 (3.8)
Hepatocellular carcinoma	81 (22.3)
Hepatitis C	59 (16.2)
Hepatitis B	8 (2.2)
MASH	87 (23.9)
Primary sclerosing cholangitis	33 (9.1)
Primary biliary cholangitis	17 (4.7)
Other	12 (3.3)
TEG platform
TEG 5000	246 (67.6)
TEG 6s	118 (32.4)
Type of transplant
Deceased donor liver transplant	329 (90.4)
Living donor liver transplant	35 (9.6)
Donor type
Donation after brain death	253 (69.5)
Donation after circulatory death	76 (20.9)
Living donor	35 (9.6)
Tranexamic acid used
Pre-anhepatic	62 (17.0)
Anhepatic	11 (3.0)
Post-reperfusion	108 (29.7)
Quantity of intraoperative blood product units
Packed red blood cells	4.4 ± 6.4
Cell saver units	4.0 ± 4.7
Fresh frozen plasma	5.8 ± 6.7
Cryoprecipitate	1.6 ± 1.9
Platelets	1.0 ± 1.3
Intraoperative CVVH	23 (6.3)
ICU length of stay, days	4.8 ± 15.6
Intubated upon ICU admission	143 (39.3)
Mechanical ventilation duration, hours	22.1 ± 23.2
ICU transfusion within 72 hours
Packed red blood cells	147 (40.3)
Fresh frozen plasma	135 (37.08)
Cryoprecipitate	116 (31.8)
Platelets	83 (22.8)
Need for re-operation within 7 days	37 (10.2)
Mortality at 30 days	3 (0.8)

OLT: Orthotopic liver transplantation; MELD-Na: Model end-stage liver disease sodium; MASH: Metabolic dysfunction–associated steatohepatitis; TEG: Thromboelastography; CVVH: Continuous veno-venous hemofiltration; ICU: Intensive care unit.