Rethinking procurement biopsy in donors with normal renal function: A barrier to kidney utilization without survival benefit

Table 1 Demographic data for deceased donor kidneys recovered for transplantation with normal renal function, n (%)/median (interquartile rage)

Characteristics	Not biopsied (n = 84589)	Biopsied (n = 73776)	P value1
Kidney			< 0.001
Dual/en bloc	2266 (2.7)	1014 (1.4)
Left	41450 (49.0)	36067 (48.9)
Right	40873 (48.3)	36695 (49.7)
Age, years	30 (21-40)	53 (43-60)	< 0.001
Male	55255 (65.3)	43675 (59.2)	< 0.001
Blood type			< 0.001
A	30963 (36.6)	28175 (38.2)
AB	2901 (3.4)	2680 (3.6)
B	9576 (11.2)	8326 (11.3)
O	41144 (48.6)	34591 (46.9)
Height, cm	173 (163-180)	170 (163-178)	< 0.001
Weight, kg	75.7 (63.5-89.9)	82.0 (69.0-98.6)	< 0.001
History of hypertension	10295 (12.2)	38077 (51.6)	< 0.001
Diabetes mellitus	1709 (2.0)	13900 (18.8)	< 0.001
DCD	18677 (22.1)	33835 (45.9)	< 0.001
COD: CVA/stroke	11818 (14.0)	26300 (35.7)	< 0.001
Creatinine terminal	0.8 (0.6-1.0)	0.8 (0.6-1.0)	0.16
eGFR terminal, mL/minute/1.73 m2	115.7 (93.8-130.6)	100 (80.0-111.9)	< 0.001
KDRI	1.00 (0.88-1.17)	1.44 (1.21-1.71)	< 0.001
KDPI, %	20 (9-38)	62 (42-79)	< 0.001
Disposition			< 0.001
Transplanted	80876 (95.6)	52952 (71.8)
Discarded	3713 (4.4)	20824 (28.2)

¹Categorical variables were compared using χ² or Fisher’s exact test, as appropriate. Continuous variables were compared using the Wilcoxon rank-sum test.

DCD: Donor after circulatory death; COD: Cause of death; CVA: Cerebrovascular accident; eGFR: Epidermal growth factor receptor; KDRI: Kidney Donor Risk Index; KDPI: Kidney Donor Profile Index.