Not just another shot: Tailoring vaccination in the era of modern liver transplantation

doi:10.5500/wjt.v16.i2.118012

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World Journal of Transplantation

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2220-3230

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Transplant. Jun 18, 2026; 16(2): 118012
Published online Jun 18, 2026. doi: 10.5500/wjt.v16.i2.118012

Table 3 Coronavirus disease 2019 vaccines (adult)-recommended use and clinical notes in chronic liver disease/Liver transplantation

Vaccine (brand)	Recommended adult use	Clinical notes in CLD/LT
Pfizer–BioNTech (Comirnaty^®; mRNA)	Updated/seasonal dose(s) per national guidance for adults	Preferred platform for most CLD/LT due to strong effectiveness and safety experience. Responses may be attenuated and additional boosters often needed
Moderna (Spikevax^®; mRNA)	Updated/seasonal dose(s) per national guidance for adults
AstraZeneca (Vaxzevria^®; viral vector)	Where available/used: 2-dose primary series per local policy; boosters typically with an updated vaccine	Generally not first-line for immunocompromised patients. Heterologous boosting with mRNA may improve breadth of responses

CLD: Chronic liver disease; LT: Liver transplantation.

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Citation: Papic N, Kosuta I, Ljubas D, Vrsaljko N, Sesa V, Domislovic V, Ahsan S, Mrzljak A. Not just another shot: Tailoring vaccination in the era of modern liver transplantation. World J Transplant 2026; 16(2): 118012
URL: https://www.wjgnet.com/2220-3230/full/v16/i2/118012.htm
DOI: https://dx.doi.org/10.5500/wjt.v16.i2.118012

Papic N, Kosuta I, Ljubas D, Vrsaljko N, Sesa V, Domislovic V, Ahsan S, Mrzljak A. Not just another shot: Tailoring vaccination in the era of modern liver transplantation. World J Transplant 2026; 16(2): 118012 [PMID: 42281865 DOI: 10.5500/wjt.v16.i2.118012]

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