Preformed vs de novo anti-human leukocyte antigens-DQ antibodies in kidney transplantation: A retrospective study

Table 2 Histological results of serial renal allograft biopsies in case 4, according to the Banff classification

Date (post-transplant)	Glomerulitis	Interstitial inflammation	Tubulitis	Intimal arteritis	Chronic glomerulopathy	Mesangial matrix expansion	Total interstitial inflammation	Interstitial fibrosis	Tubular atrophy	Vascular intimal fibrous thickening	Peritubular capillaritis	Other parenchymal tubular lesions	Arteriolar hyalinosis	C4d	Conclusion
January 2016 (day 11)	0	0	0	0	0	0	0	NR	0	0	NR	0	0	Negative	Isolated tubular epithelial lesion
April 2019 (4 years)	0	0	0	0	0	0	NR	1	1	0	3	NR	1	Positive	Active ABMR
January 2020 (5 years)	0	0	0	0	0	0	0	1	1	0	2	NR	2	Positive (focal)	Active ABMR

0: Lesion evaluated and absent; 1: Mild; 2: Moderate; 3: Severe; NR: Not reported; C4d: Complement component 4d; ABMR: Antibody-mediated rejection.