Incidence, risk factors and survival outcomes of post-transplant tertiary hyperparathyroidism in kidney recipients

Figure 3 Adjusted survival analysis comparing outcomes in kidney transplant recipients with post-transplant tertiary hyperparathyroidism vs those without tertiary hyperparathyroidism. A: Death-censored graft survival was significantly lower in patients with tertiary hyperparathyroidism (tHPT) [adjusted hazard ratio (aHR) = 3.41, 95%CI: 2.09-5.59, P < 0.001], adjusted for age, donor type, acute rejection, and baseline estimated glomerular filtration rate (eGFR); B: All-cause graft survival was significantly reduced in the tHPT group (aHR = 2.51, 95%CI: 1.78-3.53, P < 0.001), adjusted for age, acute rejection, baseline eGFR, and post-transplant smoking; C: Recipient survival was also significantly lower in the tHPT group (aHR = 1.94, 95%CI: 1.25-3.01, P = 0.003), adjusted for age, pre-transplant diabetes, dialysis duration, history of acute rejection, baseline eGFR, and post-transplant smoking. aHR: Adjusted hazard ratio; eGFR: Estimated glomerular filtration rate; tHPT: Tertiary hyperparathyroidism.