©The Author(s) 2025.
World J Transplant. Dec 18, 2025; 15(4): 108982
Published online Dec 18, 2025. doi: 10.5500/wjt.v15.i4.108982
Published online Dec 18, 2025. doi: 10.5500/wjt.v15.i4.108982
Table 4 Cost of main B-cell, T-cell, and complement-targeted therapies in Italy
| Active substance | Dosage form | Trade name | Manufacturer brand | Price per unit (€) |
| Rituximab | 500 mg, 50 mL | Mabthera | Roche | 2067 |
| Ofatumumab | 20 mg, 0.4 mL | Kesimpta | Novartis | 2035 |
| Ocrelizumab | 300 mg, 10 mL | Ocrevus | Roche | 9309 |
| Ublituximab | 150 mg, 6 mL | Briumvi | Neuraxpharm | 5067 |
| Obinutuzumab | 1000 mg, 40 mL | Gazyvaro | Roche | 4668 |
| Daratumumab | 1800 mg, 15 mL | Darzalex | Janssen-Cilag | 8418 |
| Bortezomib | 3.5 mg | Bortezomib BV | Sandoz | 1277 |
| Alemtuzumab | 12 mg, 1 mL | Lemtrada | Sanofi | 13126 |
| Thymoglobulin | 50 mg, 10 mL | Thymoglobuline | Sanofi | 239 |
| Basiliximab | 20 mg, 5 mL | Simulect | Novartis | 1515 |
| Belimumab | 400 mg | Benlysta | GlaxoSmithKline | 726 |
| Eculizumab | 300 mg, 30 mL | Soliris | Alexion | 6852 |
| Ravulizumab | 100 mg, 11 mL | Ultomiris | Alexion | 27407 |
| Imlifidase | 11 mg | Idefirix | Hansa Biopharma | 245084 |
| Intravenous human polyclonal immunoglobulin | 10 g, 200 mL | Ig vena | Kedrion | 1073 |
| Fresh-frozen plasma | 200 mL | Octaplas | Octapharma | 75 |
- Citation: Favi E, Morabito M. Obinutuzumab in kidney transplantation: Past, present, and future. World J Transplant 2025; 15(4): 108982
- URL: https://www.wjgnet.com/2220-3230/full/v15/i4/108982.htm
- DOI: https://dx.doi.org/10.5500/wjt.v15.i4.108982