Clinical impact of early graft function in kidney transplant recipients on long-term dialysis: A retrospective cohort study

Table 4 Univariate and multivariate Cox regression analysis of risk factors associated with death after transplantation¹

Variables	Factors	Univariate analysis			Multivariate analysis
		HR	95%CI	P value	HR	95%CI	P value
Age (years)	Increase of 1 year	1.069	1.022-1.118	0.003	1.058	1.002-1.116	0.040
Gender	Male vs female	2.087	0.673-6.475	0.203	-
Donor gender	Male vs female	1.171	0.436-3.146	0.755
BMI (kg/m2)	Increase of 1 kg/m2	0.993	0.864-1.142	0.927	-
Dialysis duration (years)	Increase of 1 year	1.076	1.021-1.134	0.006	NE
Pre-Tx DM	Present vs absent	1.089	0.243-4.881	0.912	-
Malignancy	Present vs absent	6.139	2.170-17.369	< 0.001	NE
Post-Tx CVD	Present vs absent	17.775	6.421-49.206	< 0.001	20.264	6.052-67.850	< 0.001
Best S-Cr (mg/dL)	Increase of 1 mg/dL	2.949	1.704-5.104	< 0.001	4.155	2.234-7.730	< 0.001

¹Multivariate analysis was performed using the Cox multivariate proportional hazard regression model with stepwise method (forward, likelihood ratio).

HR: Hazard ratio; BMI: Body mass index; pre-Tx DM: Pre-transplant diabetes mellitus; post-Tx CVD: Post-transplant history of cardiovascular disease; Best S-Cr: Lowest serum creatinine level within 3 months of transplantation; NE: Not entered.