Dietary interventions vs octreotide for post liver transplantation chylous ascites: A scoping review

Table 2 summarizes the quality of the included studies

Ref.	Study design	Sample size	Patient age range	Intervention(s)	Outcomes reported	Quality assessment (e.g., bias, limitations)
Wang et al[40]	Retrospective cohort	63	31-83 years	MCT + enteral nutrition + LFD	58 fully recovered	Retrospective design may introduce selection bias
Pan et al[25]	Retrospective cohort	58	Undisclosed	MCT + LFD (8/36); octreotide (36/58); TPN (12/36)	Immediate CA decrease with somatostatin	Retrospective; potential confounding factors not controlled
Miserachs et al[41]	Retrospective Cohort	317	2.8 years (range not specified)	LFD or MCT diet (94%); IV octreotide (6%)	Nutritional interventions did not reduce drain losses	Large sample size; retrospective design may lead to bias
Matsuura et al[8]	Retrospective cohort	94	10.8 ± 3.6 days	LFD containing MCT; TPN + Octreotide	Reduced drainage volume; resolution after 19.5 ± 7.6 days	Retrospective, but included a control group
Shapiro et al[28]	Case study	1	55 years	Fasting, Somatostatin analog, TPN	Complete resolution after 2 days	Single case; limited generalizability
Ünlüsoy Aksu et al[10]	Case study	1	11 months	Fasting + diuretics + somatostatin	Complete resolution after 21 days	Single case; limited generalizability
Baran et al[1]	Case study	2	3.5-5 years	TPN + somatostatin	Complete resolution after 7 days	Small sample size; findings may not be applicable to larger populations
Ijichi et al[42]	Case study	1	40 years	LFD + somatostatin	No resolution after 104 days, improvement with TPN	Single case; limited generalizability
Mukerji et al[36]	Case study	1	62 years	LFD + 12-hour TPN + octreotide	No resolution after 2 weeks; improvement with octreotide	Single case; limited generalizability
Chen et al[29]	Case study	1	56 years	TPN + somatostatin + sirolimus	Complete CA clearance after 30 days	Single case; limited generalizability
Saab et al[43]	Case study	1	49 years	LFD + MCT	Complete resolution after 2 months	Single case; limited generalizability
Shiba et al[16]	Case study	1	46 years	TPN + LFD	Complete resolution after 2 months	Single case; limited generalizability
Saucedo-Crespo et al[44]	Case Study	1	49 years	LFD - high protein diet	Complete CA resolution after 4 days	Single case; limited generalizability

Study design indicates whether the study is a cohort study or a case study. Sample size: The number of participants included in the study. Patient age range: Age range or specific age of patients involved in the study. Intervention(s): Treatment(s) used in the study for managing chylous ascites. Outcomes reported: Key outcomes or results reported in the study. Quality assessment: A brief overview of potential biases or limitations associated with the study design. TPN: Total parenteral nutrition; LFD: Low fat diet; MCT: Medium-chain triglycerides; CA: Chylous ascites.